Search on: RECEPTORS, SIGMA OPIOID 
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Descriptor English:   Receptors, sigma 
Descriptor Spanish:   Receptores sigma 
Descriptor Portuguese:   Receptores sigma 
Synonyms English:   Opioid Receptors, sigma
Receptor, sigma
Receptors, Opioid, sigma
Receptors, sigma Opioid
sigma Opioid Receptors
sigma Receptor
sigma Receptors  
Tree Number:   D12.776.543.750.695.620.775
D12.776.543.750.720.600.610.775
D12.776.543.750.750.555.610.775
Definition English:   A class of cell surface receptors recognized by its pharmacological profile. Sigma receptors were originally considered to be opioid receptors because they bind certain synthetic opioids. However they also interact with a variety of other psychoactive drugs, and their endogenous ligand is not known (although they can react to certain endogenous steroids). Sigma receptors are found in the immune, endocrine, and nervous systems, and in some peripheral tissues. 
History Note English:   93; was SIGMA RECEPTOR (NM) 1981-92 
Allowable Qualifiers English:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Record Number:   30546 
Unique Identifier:   D017480 

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